Flapless application of enamel matrix derivative in periodontal retreatment: A multicentre randomized feasibility trial
نویسندگان
چکیده
Aim To investigate the potential benefit of enamel matrix derivative (EMD) as adjunct to re-instrumentation residual pockets persisting after steps 1 and 2 periodontal therapy. Material Methods 44 adult patients participated in a multicentre feasibility randomized clinical trial with split-mouth design. They had presented at re-evaluation initial non-surgical therapy (steps therapy) for generalized periodontitis least teeth probing pocket depths (PPD) ≥5 ≤8 mm, bleeding on (BOP). Two similar PPD were receive either (test) or without (control) adjunctive flapless administration EMD. Differences changes BOP from baseline 6 12 months analysed, frequencies closure (PPD ≤4 mm no BOP) compared. Results For primary outcome “change mean months,” significant additional 0.79 ± 1.3 (p < .0001) could be observed test group. At months, this difference maintained (0.85 1.1 mm; p .0001). The frequency group was 69% 80% significantly higher than control 34% 42%, respectively .01). Conclusions results present study indicate EMD during retreatment (step 3 deep pockets.
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ژورنال
عنوان ژورنال: Journal of Clinical Periodontology
سال: 2021
ISSN: ['0303-6979', '1600-051X']
DOI: https://doi.org/10.1111/jcpe.13438